Ms. magazine  -- more than a magazine a movement

SIGN UP FOR MS. DIGEST, JOBS, NEWS AND ALERTS

FEMINIST WIRE NEWSBRIEFS

ABOUT
SEE CURRENT ISSUE
SHOP MS. STORE
MS. IN THE CLASSROOM
FEMINIST DAILY WIRE
FEMINIST RESOURCES
PRESS
JOBS AT MS.
READ BACK ISSUES
CONTACT
RSS (XML)
 
feminist wire | daily newsbriefs

July-30-99

Breast Cancer Drug can Advance Disease

Scientists have found evidence that tamoxifen, the drug widely used to treat breast cancer, may lose its effectiveness over time and begin to behave like the hormone it is supposed to block. Tamoxifen works by blocking the action of estrogen and keeping it from attaching to a receptor on the surface of the cell.

Researchers at Duke University Medical Center have found that after a period of two to five years, the "anti-estrogen effect of tamoxifen fades, often allowing estorgen-sensitive cancers to start growing again." The primary author of the study, John D. Norris, explained that "over time, the drug causes the estrogen receptor on cells to change and form a pocket-like structure that allows other proteins to bind there. The action of these proteins somehow changed the cellís reaction to tamoxifen. The drug converts from an anti-estrogen effect to a pro-estrogen effect."

However, the scientists have discovered that the action can be reversed with the use of peptides. They also believe that this will allow them the opportunity to find a new drug anti-estrogen drug that does not have the same effects as tamoxifen

Media Resources: Nando Times and Reuters - July 29, 1999


© Feminist Majority Foundation, publisher of Ms. magazine

If you liked this story, consider making a tax-deductible donation to support Ms. magazine.

 

 

Send to a Friend
Their
Your
Comments
(optional)


More Feminist News

12/19/2014 Woman on Life Support Revives Ireland Abortion Debate - Debate surrounding Ireland's ban on abortion has come up again following a current case involving a woman who is being kept on life support because she is pregnant. The woman's family wants her to be taken off life support, but doctors refuse because Irish law says they must do what they can to protect the 16-week-old fetus. . . .
 
12/19/2014 DC City Council Unanimously Approves Reproductive Health Anti Discrimination Bill - Wednesday, the Washington, DC City Council unanimously passed a bill that will prohibit employer interference in the reproductive health decisions of their employees. The Reproductive Health Non-Discrimination Amendment Act of 2014 was first introduced by DC Councilmember David Grosso (I-At Large), just ahead of the Supreme Court's ruling in favor of for-profit retail chain Hobby Lobby this summer. . . .
 
12/19/2014 Incremental Gains for Women in Congress - When the 114th Congress is sworn into office on January 3rd, 2015, there will be exactly the same number of women in Senate as the year before, 20, and a record-high number of women in the US House, 84. . . .