Ms. magazine  -- more than a magazine a movement

SIGN UP FOR MS. DIGEST, JOBS, NEWS AND ALERTS

FEMINIST WIRE NEWSBRIEFS

ABOUT
SEE CURRENT ISSUE
SHOP MS. STORE
MS. IN THE CLASSROOM
FEMINIST DAILY WIRE
FEMINIST RESOURCES
PRESS
JOBS AT MS.
READ BACK ISSUES
CONTACT
RSS (XML)
 
feminist wire | daily newsbriefs

July-30-99

Breast Cancer Drug can Advance Disease

Scientists have found evidence that tamoxifen, the drug widely used to treat breast cancer, may lose its effectiveness over time and begin to behave like the hormone it is supposed to block. Tamoxifen works by blocking the action of estrogen and keeping it from attaching to a receptor on the surface of the cell.

Researchers at Duke University Medical Center have found that after a period of two to five years, the "anti-estrogen effect of tamoxifen fades, often allowing estorgen-sensitive cancers to start growing again." The primary author of the study, John D. Norris, explained that "over time, the drug causes the estrogen receptor on cells to change and form a pocket-like structure that allows other proteins to bind there. The action of these proteins somehow changed the cellís reaction to tamoxifen. The drug converts from an anti-estrogen effect to a pro-estrogen effect."

However, the scientists have discovered that the action can be reversed with the use of peptides. They also believe that this will allow them the opportunity to find a new drug anti-estrogen drug that does not have the same effects as tamoxifen

Media Resources: Nando Times and Reuters - July 29, 1999


© Feminist Majority Foundation, publisher of Ms. magazine

If you liked this story, consider making a tax-deductible donation to support Ms. magazine.

 

 

Send to a Friend
Their
Your
Comments
(optional)


More Feminist News

11/21/2014 STATEMENT: Feminist Majority Foundation Applauds President's Executive Order on Immigration - Statement from Eleanor Smeal, Feminist Majority Foundation president: "The Feminist Majority Foundation applauds President Obama for taking much needed executive action to help fix our broken immigration system that has for too long torn hardworking families apart. . . .
 
11/21/2014 Fifth Circuit Court Refuses to Reconsider Ruling Blocking Mississippi TRAP Law - The full US Court of Appeals for the Fifth Circuit on Thursday refused to reconsider a panel decision blocking enforcement of a Mississippi law that threatened to close the last remaining abortion clinic in the state. In July, a panel of the Fifth Circuit Court of Appeals upheld a preliminary injunction against a Mississippi TRAP (Targeted Regulation of Abortion Providers) law requiring abortion providers to obtain admitting privileges at local hospitals. . . .
 
11/21/2014 UN Expert Calls for Action To End Violence Against Women in Afghanistan - United Nations Special Rapporteur on Violence against Women Rashida Manjoo returned last week from a nine-day official visit in Afghanistan with a call to the Afghan Government and the international community to continue its focus on creating sustainable solutions to reduce violence against women. This was Manjoo's third visit to Afghanistan, and the Special Rapporteur noted many positive developments since her travel to the country in 1999, during the Taliban regime, and in 2005. In particular, Manjoo cited the creation of the Elimination of Violence Against Women Law (EVAW) by presidential decree in 2009 as "a key step towards the elimination of violence against women and girls."EVAW criminalizes 22 acts of violence against women - including rape, child and forced marriage, domestic violence, trafficking, and forced self-immolation - and specifies punishment for perpetrators. . . .